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Minerva Anestesiologica 2011 March;77(3):366-70

Copyright © 2011 EDIZIONI MINERVA MEDICA

language: English

Use of hypothermia for traumatic brain injury: point of view

Farag E. 1, Manno E. M. 2, Kurz A. 3

1 General Anesthesia and Outcomes Research, Cleveland Clinic, Cleveland, OH, USA; 2 Cerebrovascular Center, Cleveland Clinic, Cleveland, OH, USA; 3Outcomes Research, Cleveland Clinic, Cleveland, OH, USA


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Traumatic brain injury (TBI) is one of the major causes of disability in modern society. The World Health Organization has predicted that, by 2020, traffic accidents will represent the greatest burden of global disease and injury. Brain injury after trauma occurs in two stages. Primary injury is directly associated with the biomechanical effects of the trauma, whereas secondary injury occurs later and can be attributed to processes that develop within the brain. Currently, there is no consensus for the use of hypothermia in the treatment of secondary injury after TBI. Until the results of ongoing studies are published, maintaining normothermia and avoiding hyperthermia should be used in managing patient with TBI.

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