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Minerva Anestesiologica 2010 June;76(6);463-5

Copyright © 2010 EDIZIONI MINERVA MEDICA

language: English

Prolonged neurological burden in severe lithium intoxication

Giuliani E., Iseppi D., Orlandi M. C., Alfonso A., Barbieri A.

1 Anesthesia and Intensive Care, University of Modena and Reggio Emilia, Modena, Italy; 2 Intensive Care Unit, Department of Emergency, Policlinico Hospital, Modena, Italy; 3 Intensive Care Unit, Department of Emergency, University of Modena and Reggio Emilia, Modena, Italy


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A 53-year-old woman was brought to the Emergency Department for a persistent state of stupor, tremors, fever and oliguria. The patient had been under treatment for depression. The electrocardiogram showed a wider QRS complex; laboratory tests were as follows: urea 110 mg/dL, creatinine 3 mg/dL, sodium 135 mEq/L, potassium 4.5 mEq/L, and lithium 8.0 mEq/L. Renal replacement was initiated to normalize plasma lithium levels; both stupor and speech impairment persisted for several days after dialysis. Complete recovery was achieved several days afterwards.

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