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Minerva Anestesiologica 2008 April;74(4):145-8

Copyright © 2008 EDIZIONI MINERVA MEDICA

language: English

Failure of an Abiomed left ventricular assist device in association with factor VIIa administration

Reade M. C. 1, Toyoda Y. N. 2, Murray H. N. 1

1 Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; 2 Department of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA


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Factor VIIa might be a useful treatment for coagulopathy and massive hemorrhage following implantation of a mechanical circulatory assist device, but there is a theoretical risk of device thrombosis. To date this complication has not been reported. We describe the first case of clotting of a left ventricular assist device immediately after administration of factor VIIa.

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