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Minerva Anestesiologica 1999 October;65(10):737-40

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: English

Prolonged mivacurium-induced neuromuscular block. Case report

Arcioni R., Sanfilippo M., Romano R., Lappa A., Mercieri M., Muller T. M., Marcotullio D.

Anesthesia and Intensive Care Medicine Institute, University of Rome, “La Sapienza”, Rome


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A 38-­year-old ­white ­male ­patient was ­admitted to the hos­pital for elec­tive sur­gery. Gen­eral anes­thesia was per­formed ­with pro­pofol, alfen­tanil, ­nitrous ­oxide and miv­a­cu­rium as neu­ro­mus­cular ­blocker. ­Seven ­months ­before he had the ­same sur­gery ­without anes­thetic prob­lems (he ­received: pro­pofol, vec­u­ro­nium bro­mide, fen­tanil, ­nitrous ­oxide). Neu­ro­mus­cular mon­i­toring was car­ried out ­because the ­patient was ­included in a ­study ­assessing the clin­ical ­effect of miv­a­cu­rium in micro­la­ryn­gos­copy sur­gery. ­After miv­a­cu­rium admin­is­tra­tion the ­first ­signs of ­recovery ­from neu­ro­mus­cular ­block ­were ­observed ­after 255 min. The tra­cheal ­tube was with­drawn ­after 410 min ­from miv­a­cu­rium admin­is­tra­tion, at ­this ­time the T1 was 80% of the con­trol ­values and 7 min ­later the T1 ­reached 98%.

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