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IVth SECTION
MONITORING, NEURORIANIMATION, SYSTEMIC HOMEOSTASIS, VASOSPASM TREATMENTS  PROCEEDINGS OF THE VIDEOCONFERENCE - October 5, 1996
SUBARACHNOID HEMORRHAGE: A MULTIDISCIPLINARY APPROACH - II
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Minerva Anestesiologica 1998 May;64(5):217-20

Copyright © 1998 EDIZIONI MINERVA MEDICA

language: Italian

Prevention and treatment of vasospasm in SAH-patients

Tomasello F., D’Avella D.

Università degli Studi - Messina, Clinica Neurochirurgica


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The overall data concerning the incidence of angiographyc and clinical vasospasm are reported. Furtheremore, the pathogenetic mechanisms of vasospasm with regard to vasotoxic agents, vasogenic agents and CSF blockage are discussed together with the mechanisms affecting platelet aggregation, decrease of prostacyclins, and increase of endothelin. At present, therapeutic golden standard, i.e. (triple H therapy), calcium-antagonist, fibrinolitics and antioxidizing agents are debated concerning their clinical applications, first, during and after any possible surgical or endovascular treatment of the source of bleeding, i.e., the aneurysm.

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