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Minerva Ophthalmology 2021 June-December;63(2-4):18-23

DOI: 10.23736/S2785-1265.22.01845-6

Copyright © 2022 EDIZIONI MINERVA MEDICA

language: English

Dry eye syndrome and cataract surgery: the role of vitamin D

Elena OLIARO

University of Turin, Turin, Italy



Modern cataract surgery with the use of small incisions offers excellent quality with extremely satisfactory clinical results accompanied by a rapid post-operative recovery and a reduced risk of complications. Despite the technological innovations in cataract surgery over the past half century have determined a positive impact on the quality of life (QOL) in millions of individuals around the world, however, potential complications can occur which can be responsible for alterations in vision. Dry eye syndrome is a pathology that is increasing in percentage: subjects over the age of 50 can be affected with a percentage between 20% and 30% with an almost double incidence in females. The current SARS-CoV-2 pandemic can aggravate dry eye syndrome as the mask used to protect against the virus can cause visual disturbances. For the treatment of post-operative iatrogenic dry eye syndrome, tear substitutes with antioxidant action without preservatives have proven to be very effective. In particular, formulations containing ginkgo biloba extract, containing specific substances such as procyanidins, prodelfinins and terpenes, have demonstrated a cytoprotective activity against cells subjected to photoablative stress, contributing to a more rapid and regular regeneration of the subepithelial nerve plexus as well as the use topical eye drops based on active ingredients such as vitamin D, vitamin A, omega 3 fatty acids and liposomes may be able to reduce post-operative discomfort, especially related to dry eye syndrome.


KEY WORDS: Cataract; Dry eye syndrome; Ophthalmic surgery; vitamin D

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