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La Rivista Italiana della Medicina di Laboratorio 2020 Settembre;16(3):177-81

DOI: 10.23736/S1825-859X.20.00074-2

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: Italian

Pregnancy proteinuria evaluation

Vincenzo BRESCIA ¹, Rosalba RUTA ² ✉, Luigi CECI ²

¹ UOC Medicina di Laboratorio, A.O. Pia Fondazione Panico, Tricase, Lecce, Italia; ² UOC Patologia Clinica e Microbiologia, Ospedale Bonomo, Azienda Sanitaria Locale Barletta Andria Trani, Andria, Italia

This communication summarizes recommendations proposed by National Institute for Health and Care Excellence in June 2019, whose aim was the protein/creatinine ratio (PCR) and albumin/creatinine ratio (ACR) measurements and critical threshold on spot urine samples. These tests are rapid, sensitive and accurate in detecting significant proteinuria in pregnant women, as a risk factor for pre-eclampsia. These assays could replace proteinuria test on 24 hours urine collection, no longer recommended as a first level test.

KEY WORDS: Protein/creatinine ratio (PCR); Albumin/creatinine ratio (ACR); Proteinuria; Albuminuria; Pre-eclampsia