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Medicina dello Sport 2018 December;71(4):561-78

DOI: 10.23736/S0025-7826.18.03431-2

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English, Italian

Resistance training influences Adipokines and various biochemical factors altering the risk of metabolic syndrome in young male obese students

Prasanna RAJAGOPALAN 1 , Snehil DIXIT 2, Khalid ALAHMARI 2, Charles STEPHEN DEVENESAN 1, Kanagaraj RENGARAMANUJAM 2, Gaffar SARWAR ZAMAN 1, Hateem ALI ASIRI 1, Harish C. CHANDRAMOORTHY 3

1 Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia; 2 Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia; 3 Center for Stem Cell Research and Department of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia



BACKGROUND: Young obese adults have a very high risk of developing metabolic syndromes (MetS). The predisposing factors like adipokines, lipid profile, inflammatory cytokines and antioxidant enzyme status between the sedentary and active life style in young obese individuals have not been elaborately studied. The physiological relationship and impact of resistance trainings over obesity inducing factors in young male obese individuals who are at risk for metabolic syndrome (Mets) were evaluated.
METHODS: Blood samples were collected before and at different time points of light to moderate and resistance trainings. Adipocytokines, obesity hormones, pro-inflammatory cytokines, lipid profile and antioxidant enzymes were measured using standard spectrophotometric and ELISA methods.
RESULTS: A proportional increase in adiponectin and HLD-c has been observed post 5th and 10th weeks with respect to control groups. A gradual decrease in lecithin, resistin, SOD, GPx along with TNFα and IL-6 were hall mark observations post 5th and 10th week resistance training. There was no significant alternation in obesity inducing factors for non-obese control and light to moderate exercise groups.
CONCLUSIONS: Resistance training proves beneficial in lowering obesity inducing factors in young obese adults.


KEY WORDS: Adiponectin - Leptin - Metabolic syndrome - Obesity - Resistin - Resistance training

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