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Medicina dello Sport 2017 December;70(4):495-502

DOI: 10.23736/S0025-7826.17.03056-3

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English, Italian

Evaluation of the antioxidant effects of lycopene supplementation in athletes by high performance liquid chromatography

Qiuping ZHANG 1, Jianheng ZHENG 1, 2, Jun QIU 1, Xiahong WU 1, Yangshuo XU 1, Mengwei SUN 1

1 Key Laboratory of State General Administration of Sport, Shanghai Research Institute of Sports Science, Shanghai, China; 2 Key Laboratory of Public Health Safety, Department of Nutrition and Food Hygiene, School of Public Health, Fudan University, Shanghai, China


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BACKGROUND: The study was aimed to evaluate the antioxidant effect of lycopene supplementation in athletes by determining the concentration level of malondialdehyde (MDA) in plasma by high performance liquid chromatography (HPLC) for the first time.
METHODS: In this study, 14 female athletes were recruited and randomly divided into control and treated group. The treated group was administered with lycopene capsule continuously for 30 days during one period with high intensity of training, while the control group was administered with placebo instead. The plasma levels of MDA before and after the administration were detected by an HPLC method.
RESULTS: The lycopene can significantly reduce the rise of MDA level in the treated group when compared to that in control group (4.91±0.31 vs. 5.78±0.65 μmol·L-1, P<0.01).
CONCLUSIONS: Lycopene supplementation has antioxidant effect in professional athletes.


KEY WORDS: Malondialdehyde - Lycopene - Athletes - Chromatography, high pressure liquid - Oxidative stress

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