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Medicina dello Sport 2003 June;56(2):115-22


language: Italian

The role of the electroion-therapy in the modulation of some biochemical factors, of the fibronectine and the factor XIII in the repairing processes of acute and chronic lesions: hypothesis of work

Francavilla G. 1, Parisi A. 1, Schembri B. 1, Giglio A. 3, Caracciolo C. 2, Pancucci G. 1, Matina A. 1, Cristofalo M. 1, Francavilla V. C. 1

1 Cattedra di Medicina dello Sport, Università degli Studi di Palermo, Palermo; 2 Divisione di Ematologia con TMO, Università degli Studi di Palermo, Palermo; 3 AUSL n. 6 Palermo, Servizio di Medicina dello Sport, Palermo


Physiological research­es ­have ­shown ­that ­electric cur­rents (with a ion­ic ­flow mod­i­fy the arte­ri­al cir­cu­la­tion stim­u­lat­ing in ­this way a bet­ter sprink­ling of tis­sues allow­ing the speed­ing up of the bio­phis­i­cal and bio­chem­i­cal mech­a­nisms.
These mech­a­nisms stim­u­late the ome­os­ta­sis, and there­fore ­they ­restore the phys­io­log­i­cal con­trol of the appa­ra­tus the elec­tro­mag­net­ic stim­u­li are direct­ed to.
It is ­known ­that ­electric and mag­net­ic sig­nals ­reach the eucar­i­ote ­cells ­which elab­or­a­te and ­convert ­them ­into plas­mat­ic ­wall in ­order to com­bine ­them to the molec­u­lar mech­a­nisms typ­i­cal of the “com­plex build­ing” ­known as the cel­lu­lar cyto­plasm in ­order to acti­vate a lot of enzym­ic ­ducts and remod­u­late the cel­lu­lar metab­olism.
Schematically the elec­tro­ion-ther­a­py con­sists in pro­duc­ing an elec­tro­stat­ic ­field gen­er­at­ed by a ­high-ten­sion-elec­trode ­which is ­able to ­break the die­lec­tric inten­sity, creat­ing (in ­this way) an ­electric ­field ­which is so ­strong ­that ­human ­body can be con­sid­ered as an “elec­tro­lit­ic solu­tion”, ­because all its tis­sues con­tain ­some ­saline solu­tions, ­they are excel­lent con­duc­tors, and ­this cur­rent ­flows in the ­patient’s ­body and, by ­means of an arm­band, it clos­es ­itself ­again in the ­shape of ­mass. The ­increase of the selec­tive cel­lu­lar perme­abil­ity has to be con­sid­ered as a ­first ­effect ­ensued by the re-esta­blishe­ment of the phys­io­log­i­cal poten­tial dif­fer­ence of the mem­brane.
The ther­a­peu­tic effi­ca­cy ­towards the treat­ment of ede­ma, inflam­ma­tion and ­also ­pain ­would ­come ­from ­this bio­phys­i­cal ­action. The treat­ment of ­pain, inflam­ma­tion and the mend­ing of ­injured tis­sues rep­re­sent the clin­i­cal con­di­tions ­where tech­nics of elec­tro­ther­a­peu­tic ­type ­have ­been intro­duced for ­some ­time. The aim of the ­work has ­been to con­sid­er new ­fields to ­apply the elec­tro­ion- ther­a­py. First of all it has ­been ­applied to the reha­bil­i­ta­tion of ­sports pathol­o­gies, ­with an ­exact ther­a­peu­tic tar­get rep­re­sent­ed by the reduc­tion of ede­ma and of ­pain; ­then, we want­ed to try out the effi­ca­cy of the elec­tro­ion-ther­a­py in the stim­u­la­tion of the mend­ing of chron­ic or not inju­ries, of cov­er­ing ­skin tis­sues.
The ­main ­result is rep­re­sent­ed by the imme­di­ate res­o­lu­tion of ­pain, the extin­guish­ing of inflam­ma­tion, the ­quick reduc­tion of ede­ma and the speed­ing up of the for­ma­tion of gran­u­lat­ed tis­sue in ­order to ­repair inju­ries ­which ­have a trou­bled ­course, ­which ­have gen­er­al­ly ­been reluc­tant to ­heal up for a ­long ­time and ­don’t ­respond to the con­ven­ti­onal meth­ods of treat­ment. Up to now ­some bio­chem­i­cal fac­tors ­which ­take ­part in the mod­ula­tion of ­pain and the reduc­tion of the inflam­ma­to­ry ­state ­have ­been iden­ti­fied but nev­er quan­tized in labor­a­to­ry, togeth­er ­with the pro­teins or the “fac­tors” ­which con­trol the pro­cess ­increase of repair­ing tis­sues. Scientific curi­os­ity has per­suad­ed us to ­plan a ­research in ­this field­ by stud­y­ing the beha­vi­our (­after an appro­pri­ate stim­u­la­tion ­through elec­tro­ion- ther­a­py) of ­some pro­teins of the ­acute ­stage, of the fibro­nec­ti­n and of the fac­tor ­XIII sup­pos­ing ­these fac­tors can ­play a key ­role in the res­o­lu­tion of an inflam­ma­to­ry ­state and in the speed­ing up of the for­ma­tion of gran­u­lat­ed tis­sues in ­order to ­repair inju­ries ­with a trou­bled or not ­course by ­means of elec­tro­ion-ther­a­py.

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