CASE REPORT   

European Journal of Oral and Maxillofacial Surgery 2021 August;5(2):62-4

DOI: 10.23736/S2532-3466.20.00214-3

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Granular cell tumor in the maxillary mucosa

Ouakil ABDESSAMAD ✉, Chbicheb SALIHA

Department of Oral Surgery, Counseling and Dental Treatment Center, Faculty of Dental Medicine, Mohammed V University, Rabat, Morocco

Granular cell tumor or Abrikossoff tumor is a neurogenic tumor often benign origin. Cervicofacial localization is frequent. The average age for developing this lesion is between fourth and sixth decade with twice occurrence in women. It is a rare tumor (0.019 to 0.03% of all tumors) with 2% incidence of malignancy. It presents a favorable prognosis after surgical excision. but due to the rarity of this lesion, it can be mistaken with other similar lesions. The gold standard for diagnosis of granular cell tumor is histopathology since it has specific features with large polygonal to rounded cells with small nuclei, which are usually centrally located. The cytoplasm is eosinophilic with coarse granules, although sometimes the granules may be quite fine. There is often an intimate relationship with nerve. However, the biopsy should be performed carefully to avoid confusion with a malignant tumor in case of superficial biopsy. Since this disease may have no solid lesions and tumor cells can infiltrate local tissues, based on the full excision of the lesion, the extent of resection may be extended to areas without infiltration. This disease has a possibility of recurrence and patients need to be followed-up. This work aimed, through a clinical case report, at updating and discussing the aspects of diagnosis and management of granular cell tumor in oral surgery.

KEY WORDS: Granular cell tumor; Diagnosis; Mouth neoplasms; Diagnosis, differential