Home > Journals > International Angiology > Past Issues > International Angiology 2018 April;37(2) > International Angiology 2018 April;37(2):100-11

CURRENT ISSUE
 

ARTICLE TOOLS

Publication history
Reprints
Cite this article as

INTERNATIONAL ANGIOLOGY

A Journal on Angiology


Official Journal of the International Union of Angiology, the International Union of Phlebology and the Central European Vascular Forum
Indexed/Abstracted in: BIOSIS Previews, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,37


eTOC

 

REVIEW  


International Angiology 2018 April;37(2):100-11

DOI: 10.23736/S0392-9590.18.03916-0

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

The influence of patients’ nutritional status on the prevalence, course and treatment outcomes of lower limb ischemia: an overview of current evidence

Marta SPYCHALSKA-ZWOLIŃSKA 1 , Tomasz ZWOLIŃSKI 2, Marzena ANASZEWICZ 1, Jacek BUDZYŃSKI 1, 3

1 Clinic of Vascular and Internal Diseases, Jan Biziel University Hospital No. 2, Bydgoszcz, Poland; 2 Clinic of General, Gastroenterological, Colorectal and Oncological Surgery, Jan Biziel University Hospital No. 2, Bydgoszcz, Poland; 3 Department of Vascular and Internal Diseases, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland


PDF  


INTRODUCTION: The association of lower limb ischemia (LLI) with disturbances in nutritional status, in respect to over- or undernutrition, is still uncertain. The aim of this study was to present the current state of knowledge on this issue.
EVIDENCE ACQUISITION: Systematic review of papers published between 2006 and 2018.
EVIDENCE SYNTHESIS: The literature shows inconclusive evidence regarding the impact of nutritional status on the risk, course, prognosis and outcomes of conservative and invasive treatment of LLI. The majority of publications available demonstrate greater LLI prevalence in overweight and obese patients, a worse prognosis both in malnourished and severely obese patients, poorer outcomes of invasive treatment in underweight patients, and better results for endovascular and surgical treatment in patients with overweight and class I obesity, although without such a relationship for conservative therapy. Possible explanations linking nutritional status and LLI seem to be: the endocrine, paracrine, and autocrine activity of adipose tissue, a decrease in physical activity, and the effect of diet-dependent comorbidities, e.g. diabetes mellitus, hypertension and dyslipidemia.
CONCLUSIONS: There is a growing body of evidence concerning an association between LLI and patients’ nutritional status. A so-called “obesity paradox” or “BMI paradox” seems to exist among patients with LLI and mainly concerns outcomes of endovascular and surgical treatment. However, further studies are needed to evaluate the clinical importance of body composition, the distribution and endocrine activity of adipose tissue, and the effect of weight reduction and/or nutritional support in the LLI patient group.


KEY WORDS: Nutritional status - Malnutrition - Overweight - Obesity - Treatment outcome - Epidemiology

top of page

Publication History

Issue published online: March 19, 2018
Article first published online: January 31, 2018
Manuscript accepted: January 22, 2018
Manuscript revised: January 3, 2018
Manuscript received: August 31, 2017

Cite this article as

Spychalska-Zwolińska M, Zwoliński T, Anaszewicz M, Budzyński J. The influence of patients’ nutritional status on the prevalence, course and treatment outcomes of lower limb ischemia: an overview of current evidence. Int Angiol 2018;37:100-11. DOI: 10.23736/S0392-9590.18.03916-0

Corresponding author e-mail

spychalska.marta@gmail.com