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International Angiology 2009 December;28(6):452-7

Copyright © 2010 EDIZIONI MINERVA MEDICA

language: English

The risk of congestive heart failure is increased in persons with varicose veins

Mäkivaara L. A. 1, Ahti T. M. 1, Luukkaala T. 1, 2, Hakama M. 1, Laurikka J. O. 3

1 University of Tampere, Tampere School of Public Health, Tampere, Finland; 2 Science Center, Pirkanmaa Hospital District, Tampere, Finland; 3 Heart Center, Pirkanmaa Hospital District, Tampere, Finland


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AIM: Varicose veins are a common condition but their etiology and relationship with other cardiovascular diseases are not well established. The aim of the study was to find out if persons with varicose veins have a higher risk of congestive heart failure (CHF) than persons without varicose veins.
METHODS. The prevalence of CHF at entry and the incidence of CHF during a five-year follow-up period were studied in persons with and without varicose veins. A study was conducted with a questionnaire in a population of 4 903 middle-aged residents in Tampere, Finland.
RESULTS: Marginally higher prevalence of CHF was found in persons with varicose veins than in those without (2.9% vs. 1.9%) with OR 1.6 (1.0-2.3) and sex and age adjusted OR 1.2 (0.8-1.9). The incidence of CHF was higher in subjects with varicose veins than in others (4.9 vs. 2.6 per 1000 person-years) with IDR 1.9 (1.1-2.9) and sex and age adjusted IOR 2.5 (1.4-4.6). The result was further adjusted for body mass index, arterial disease and hypertension; multi-adjusted IOR for the incidence of CHF by varicose veins was 2.1 (1.1-4.0).
CONCLUSIONS: Our longitudinal observation is consistent with the hypothesis that persons with varicose veins have a higher risk of CHF which is not mediated through sex, age, overweight, arterial disease or hypertension.

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