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Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2021 March;180(3):96-8

DOI: 10.23736/S0393-3660.20.04323-5

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Extremely early intrauterine growth restriction with dramatic sFlt-1/PlGF ratio

Viktor OSHOVSKYY 1 , Kostyantyn MYLYTSYA 2

1 Uniklinika Medical Center, Kyiv, Ukraine; 2 St. Nicholas Clinic, Zaporizhzhia, Ukraine



The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) is increased in preeclampsia. The ability to accurately rule out preeclampsia, eclampsia, and the HELLP syndrome within 1 week on the basis of the sFlt-1/PlGF ratio is likely to improve clinical decisions with regard to hospitalization versus outpatient monitoring and the intensity of outpatient monitoring. The aim of this study was to present a rare case of early placental dysfunction with extremely high sFlt-1/PlGF ratio.


KEY WORDS: Placenta; Pre-eclampsia; Fetal growth retardation

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