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ORIGINAL ARTICLE   

Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2021 January-February;180(1-2):19-26

DOI: 10.23736/S0393-3660.19.04130-5

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

Indonesian heart-friendly series-I three times a week improves cardiorespiratory fitness and TNF-α protein expression in elderly

Nita FITRIA 1 , Nyoman E. LISTER 2, Mohammad GHOZALI 3, Lynna LIDYANA 4, Shelly ISKANDAR 4, Leonardo LUBIS 3, Ambrosius PURBA 3

1 Faculty of Nursing, University of Padjadjaran, Bandung, Indonesia; 2 Faculty of Public Health, University of Prima, Medan, Indonesia; 3 Faculty of Medicine, University of Padjadjaran, Bandung, Indonesia; 4 Department of Psychiatry, Rumah Sakit Dokter Hasan Sadikin, Bandung, Indonesia



BACKGROUND: Limited physical activities in the elderly can cause decreasing cardiorespiratory fitness and biomolecular changes including increased Tumor Necrosis Factor-α (TNF-α). Indonesian Heart-friendly Exercise Series-I (IHES-I) is one of the aerobic sports that can improve cardiorespiratory fitness. This study aimed to analyze the effect of IHES-I on cardiorespiratory fitness and TNF-α plasma protein expression in the elderly.
METHODS: This study used three arms experimental study with pre and post-test design that included 27 healthy older people who routinely carried out IHES-I at a Nursing Home in Indonesia. The research subjects were divided into three groups based on their exercise frequency, namely three, four, and five times a week for six weeks. The cardiorespiratory fitness was measured through the distance traveled on the 6-minute test at the first and sixth weeks. The TNF-α plasma was examined based on the ELISA method. Data were analyzed by using paired t-test so that the mean difference value would be discovered before and after exercising.
RESULTS: The elderly group who carried out IHES-I three times a week can significantly improve cardiorespiratory fitness (269.5±102.5 m vs. 375.5±79.98 m) and mean difference was -106,0; P=0.009, P<0.05. There were mean differences of TNF-α plasma protein expression between before and after exercising (423.75±66.0 pg/mL vs. 379.93±100.23 pg/mL) and mean difference was -1.70; P=0.954, P<0.05.
CONCLUSIONS: This study provides evidence that IHES-I three times a week improves better cardiorespiratory fitness and can not decrease TNF-α plasma protein expression in elderly.


KEY WORDS: Cardiorespiratory fitness; Aged; Sports

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