Home > Journals > Gazzetta Medica Italiana Archivio per le Scienze Mediche > Past Issues > Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2020 December;179(12) > Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2020 December;179(12):675-8

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Publication history
Reprints
Permissions
Cite this article as
Share

 

CASE REPORT   

Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2020 December;179(12):675-8

DOI: 10.23736/S0393-3660.20.04392-2

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Gerbode defect, Ebstein anomaly and Wolff-Parkinson-White in patient with Down Syndrome. Never say never…

Valeria PERGOLA 1, Giovanni DI SALVO 2, Sara DI MICHELE 3, Isra ELMAHI 4, Saba SEEMI 5, Domenico GALZERANO 4, 5 , Olga VRIZ 5, Reem AL SERGANI 6

1 Unit of Cardiology, Croydon University Hospital, London, UK; 2 Department of Cardiology, Royal Brompton Hospital, London, UK; 3 Division of Cardiology, San Filippo Neri Hospital, Rome, Italy; 4 Faculty of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia; 5 Unit of Cardiology, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia; 6 Faculty of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia



We described a unique case of a 15-year-old Down Syndrome female patient with a Gerbode-type ventricular septal defect, Ebstein anomaly and Wolff-Parkinson-White Syndrome. Transthoracic echocardiography allowed to correctly diagnose the structural abnormalities; it revealed Ebstein anomaly with curtain-like appearance of the anterior tricuspid valve leaflet and dilated right atrium with atrialized right ventricle with small functional right ventricle. A peri membranous ventricular septal defect, partially covered by tricuspid tissue, with a shunt from the left ventricle (LV) to the atrialized portion of the right ventricle was found. LV showed normal diameters and good systolic function. The interatrial septum was aneurysmal with a small secundum atrial septal defect with bidirectional shunt. Electrophysiological study demonstrated an atrioventricular (AV) accessory pathway that was treated by ablation. According to the literature the patient was managed conservatively. The knowledge of this association of rare pathologies will lead the clinicians to careful look for the abnormalities reported when one of these has been diagnosed. Nevertheless, this combination was never described to the best of our knowledge in Down syndrome patients.


KEY WORDS: Heart Septal Defects, Ventricular; Ebstein anomaly; Wolff-Parkinson-White syndrome; Down syndrome

top of page