CASE REPORT   

Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2020 March;179(3):197-203

DOI: 10.23736/S0393-3660.19.04152-4

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

Pulmonary nodules with crescentic glomerulonephritis. Is it always anti-neutrophil cytoplasmic antibody associated?

Alper ALP ¹ ✉, Hakan AKDAM ², Sabri BARUTÇA ³, Nezih MEYDAN ³, Yavuz YENİÇERİOĞLU ², Ibrahim METEOGLU ⁴, Taşkın ŞENTÜRK ⁵

¹ Department of Nephrology, SBU Tepecik Education and Research Hospital, Izmir, Turkey; ² Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey; ³ Division of Oncology, Department of Internal Medicine, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey; ⁴ Department of Medical Pathology, School of Medicine, Adnan Menderes University, Aydın, Turkey; ⁵ Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides can be seen with many different forms in our clinical practice. Radiological and clinical conditions with pulmonary findings constitute an important part of them. It is essential to make differential diagnosis of nodules and cavitary lung lesions clearly in these patients. Other pathologies like pulmonary infections, sarcoidosis, tuberculosis and especially lung malignancies can be challenging for accurate diagnosis. Recently, fluorine-18-fluorodeoxyglucose (FDG) PET/CT technique is increasingly used in the evaluation of nodules. In our paper, we present two different patients with similar clinical and radiological findings, resulting in two different diagnostic progresses.

KEY WORDS: Anti-neutrophil cytoplasmic antibody-associated vasculitis; Lung neoplasms; Biopsy