ORIGINAL ARTICLE   

Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2020 January-February;179(1-2):54-8

DOI: 10.23736/S0393-3660.19.04018-X

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

Clinicopathological characteristics of children with intestinal polyp in the Southwest of China

Sheng-Lan WANG ¹, Ramesh RANA ^{1, 2}, Wei-Ping SONG ¹, Cheng-Zhi HE ¹, Heng-Jun GAO ¹, Chang-Qing YANG ¹ ✉

¹ Division of Gastroenterology, Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine, Shanghai, China; ² Department of Internal Medicine, Gautam Buddha Community Heart Hospital, Butwal, Nepal

BACKGROUND: Colorectal polyp is a common cause of hematochezia in children, and juvenile polyp is the most common histological type. Although, children polyp has a good prognosis, there is still a potential risk of recurrence and malignant transformation.
METHODS: To evaluate the types of intestinal polyp in children and its’ characteristic in Southwest region of China, we retrospectively selected cases from January 2010 to August 2015 in those children who underwent colonoscopy examination.
RESULTS: The demographic characteristics revealed that the average age of children was 6.9±2.4 years with male predominance (63.1%). Hematochezia was the chief clinical symptom (N.=147, 87.5%), accompanied by recurrent abdominal pain (N.=21, 12.5%), prolapsed polyp (N.=19, 11.3%), abdominal distention (N.=2, 1.2%), and anemia (N.=13, 7.7%). Colonoscopy test showed that the rectum was the most common location of polyps (N.=134, 79.81%), including solitary polyp (N.=131, 78.4%) and multiple polyps (N.=37, 21.6%). Histopathologically, the juvenile polyp was the most prevalent histologic type (N.=147, 87.5%), followed by inflammatory polyp (N.=15, 8.9%), hyperplastic polyp (N.=5, 3.0%), and 1 case of malignant transformation (0.5%).
CONCLUSIONS: Taking together, incidence of juvenile polyp in Southwest region of China was high. With the application of electronic colonoscopy technology in Department of Pediatric gastroenterology, a growing number of children with intestinal polyp diagnosed and effectively treated. Although the risk of malignant transformation in children with juvenile polyp is considered to be few or none, it is better to excise polyp as soon as possible.

KEY WORDS: Intestinal polyps; Gastrointestinal hemorrhage; Colonoscopy; Child