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Gazzetta Medica Italiana - Archivio per le Scienze Mediche 2019 July-August;178(7-8):527-33

DOI: 10.23736/S0393-3660.18.03871-8

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Ignoring regression to the mean leads to misleading interpretation about muscle strength responsiveness in obese elderly women

Dahan da CUNHA NASCIMENTO 1, 2 , Cristiane R. da SILVA 1, Samuel C. OLIVEIRA 1, Brad J. SCHOENFELD 3, Silvana S. FUNGHETTO 4, Alessandro O. SILVA 5, 6, Renato VALDUGA 7, Jonato PRESTES 1

1 Department of Physical Education, Catholic University of Brasília, Brasília, Brazil; 2 Department of Physical Education, University Center of the Federal District (UDF), Brasília, Brazil; 3 Department of Health Sciences, CUNY Lehman College, Bronx, NY, USA; 4 Department of Nursing, University of Brasília (UNB), Brasília, Brazil; 5 University Center of Brasília (UniCEUB), Brasília, Brazil; 6 Department of Medicine and Physical Education, Integrated Colleges of the Central Plateau Educational Union (FACIPLAC), Brasília, Brazil; 7 Department of Physiotherapy, Secretary of State for Health of the Federal District, Emergency Unit, Ceilandia Regional Hospital, Brasília, Brazil



BACKGROUND: The goal of this study was to identify subjects with high, medium and low muscle strength responsiveness to resistance training and analyze if muscle strength responsiveness might be explained by the regression to the mean effect.
METHODS: Twenty-seven untrained obese elderly women (mean±SD; age = 68.37±5.55 years; weight = 67.53±10.54 kg; height = 1.55±0.05 m; fat = 39.55±5.97%) participated in the present study. The responsiveness of muscle strength was determined based on the relative handgrip strength change between the pre- and post-training time points.
RESULTS: Small measurements at baseline tend to be followed by measurements that are higher at the post-training for both high and medium when compared with the low responders.
CONCLUSIONS: The effects of the regression to the mean should always be considered as a possible cause of an observed change in future investigations addressing individual variation in training responses.


KEY WORDS: Resistance training; Aging; Exercise

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