ORIGINAL ARTICLE   

Gazzetta Medica Italiana Archivio per le Scienze Mediche 2018 December;177(12):701-6

DOI: 10.23736/S0393-3660.17.03680-4

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Vitamin D as a predictor of arrhythmia recurrence after balloon cryoablation

Levent CERIT ¹ ✉, Aziz GÜNSEL ¹, Zeynep CERIT ², Bilal GEDIZ ³, Hamza DUYGU ¹

¹ Department of Cardiology, Near East University, Nicosia, Cyprus; ² Department of Pediatric Cardiology, Near East University, Nicosia, Cyprus; ³ Department of Cardiology, Manisa State Hospital, Manisa, Turkey

BACKGROUND: The aim of this study was to evaluate of predictive value of vitamin D (vitD) for prediction of atrial fibrillation (AF) recurrence at follow-up in a group of our patients treated by balloon cryoablation.
METHODS: A total of 63 symptomatic drug-refractory AF patients who underwent pulmonary vein isolation with second-generation cryoballoon between January 2014 and July 2017 were included. Study group was divided into two group according to whether present of AF recurrence (group I) or not (group II). Association between vitD and AF recurrence was evaluated in this study population.
RESULTS: There were significant difference between two groups with regard hypertension (HT), left atrial (LA) diameter, left atrial appendage emptying peak flow velocity (LAAV), and vitD. On univariate analysis, hypertension (HT), LA diameter, LAAV, and vitD were associated with AF recurrence. On multivariate analysis LA diameter, LAAV, and vitD were independent predictors for AF recurrence (OR=2.168; 95% CI: 1.487-3.651; P<0.001, OR=2.329; 95% CI: 1.834-4.186; P<0.001, OR=1.927; 95% CI: 1.365-3.352; P<0.001, respectively).
CONCLUSIONS: In this study, it was found that vitD was independent predictor of AF recurrence after cryoballon ablation.

KEY WORDS: Atrial fibrillation - Ablation techniques - Vitamin D - Left atrial function