Home > Journals > Gazzetta Medica Italiana Archivio per le Scienze Mediche > Past Issues > Gazzetta Medica Italiana Archivio per le Scienze Mediche 2018 September;177(9):415-6 > Gazzetta Medica Italiana Archivio per le Scienze Mediche 2018 September;177(9):482-8

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Publication history
Reprints
Permissions
Cite this article as

 

ORIGINAL ARTICLE   

Gazzetta Medica Italiana Archivio per le Scienze Mediche 2018 September;177(9):482-8

DOI: 10.23736/S0393-3660.17.03598-7

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: Italian

Lipectomy as a source of stem cells

Michele P. GRIECO 1, 2 , Francesco SIMONACCI 1, 2, Nicolò BERTOZZI 1, 2, Edoardo RAPOSIO 1, 2

1 Division of Plastic Surgery, Department of Medicine and Surgery, University of Parma, Parma, Italy; 2 Unit of Dermatologic, Mini-Invasive, Regenerative, and Plastic Surgery, Parma University Hospital, Parma, Italy


PDF


Over the last few years, interest in adipose tissue as the ideal source of mesenchymal stem cells (MSCs) has considerably grown. MSCs represent the future of regenerative medicine, both for their multipotent capabilities and for their ability to excretion of pro-regenerative cytokines. Mesenchymal stem cells derived from adipose tissue (ASC) have become important in regenerative medicine due their abundance in adipose tissue and ease of liposuction extraction. To obtain adipose tissue, several harvesting techniques exist. Liposuction is a safe and reliable aesthetic surgical technique to obtaining ASC in large quantities, but few studies have highlighted the effects of different liposuction techniques on ASC regeneration capacity and their ASC functionality. Several studies have been considered that have assessed whether the various liposuction approaches could have influenced the vitality of ASCs. We also reported our ASC withdrawal and isolation techniques, which allowed us to isolate a quantity of 9.06 ×105 ASC from 100 mL of adipose tissue, with ASC yield of 25.9% of the pellet. The use of mesenchymal stem cells (MSC) in clinical research and applications has continued in recent decades. By comparing the various liposuction techniques in literature, we concluded that standard aspiration-assisted liposuction remains the most effective and least traumatic ASC extraction method.


KEY WORDS: Adipose tissue - Mesenchymal stromal cells - Lipectomy

top of page