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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2017 April;176(4):222-5

DOI: 10.23736/S0393-3660.16.03386-6

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

Nasal vascular hamartoma: differential diagnosis of nasal lesion

Raianni R. SILVA 1, Thalita G. OLIVEIRA 1, Marcos M. SILVA 2, Juliana A. CAIXETA 3

Medical Student at Centro Universitário de Anápolis, UniEvangelica, Anápolis, Goiás, Brazil; 2 Pathologist and Faculty Member of the Centro Universitário de Anápolis, UniEvangelica, Anápolis, Goiás, Brazil; 3 MS, Otolaryngologist, and Faculty Member of the Centro Universitário de Anápolis, UniEvangelica, Anápolis, Goiás, Brazil


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Hamartomas are non-neoplastic malformations caused by innate errors in tissue development or by the delayed proliferation of immature cells in the post-natal period. Here, we report a case of vascular hamartoma of the vestibule of a 23-year-old woman. Physical examination and computadorized tomography were not able to make a good hypothesis ad made the surgical planning uncertain. The immunohistochemical analysis revealed the presence of SMA, CD31, CD34, and Ki-67 and negative for AE1/AE3, desmin, p63, and S-100 protein. Although respiratory hamartomas have been described in literature, it is the first time that a nasal vascular hamartoma is described in the nasal vestibule.


KEY WORDS: Nose - Hamartoma - Antigens, CD31 - Ki-67 antigen - Soft tissue neoplasms - Chemistry

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