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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2013 April;172(4):309-15


language: Italian

Early diagnosis of ventriculomegaly in the first trimester: case report

Venezia R., Mocera G., Carta S., Cucinella G.

U.O.C. di Ostetricia, Ginecologia e Fisiopatologia della Riproduzione, Università degli Studi di Palermo, Palermo, Italia


The hydrocephalus is one of the most frequent congenital anomalies of the nervous system. The origin is multifactorial. It is associated to an increase of the fetal/neonatal morbidity/mortality. The severe hydrocephalus is often associated to an unfavorable outcome; the border-line hydrocephalus has a more favorable outcome. The management consists of monthly ultrasound controls, genetic consultation, fetal karyotype examination, evaluation of the complex TORCH infections and a possible in utero RMI. Values below 12 mm have not meant pathological, but simple physiology variation, on condition that the aneuploidy or the other anomalies are excluded. The outcome is favorable if the dilatation is unilateral, steady or into remission, if it is moderate and isolated. Our clinical case is relative to a woman of thirty-seven, to the thirteenth week and two days of gestation. Thanks to the aid of the abdominal ultrasuond a room gestational has been identified, with inside an embryo, on which all the structures to evaluate for that gestational age seem to normal,There are no sonographic markers of chromosomal abnormalities except in the cerebral ventricles in which, judged on the transventricular and sagittal plane, it should be noted a bilateral dilatation with preservation of the integrity of the midline. This shows that it may be possible early detection of an isolated ventriculomegaly already during ultrasound screening for chromosomal abnormalities in the first quarter. The evolution of these cases, however, should be followed with further testing to rule out known causes and to make a diagnosis of exclusion of mean isolated idiopathic ventriculomegaly, associated with neonatal favorable prognosis, even if restricted.

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