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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2013 March;172(3):229-32

Copyright © 2013 EDIZIONI MINERVA MEDICA

language: English

Langerhans cell histiocytosis as unifocal lesion of the cervical spine in adult age. Case report

Romeo F. 1, Toscano S. 1, Fumai V. 1, Casiello M. 2, Colella P. 3, D’agostino A. 1

1 Department of Neurosurgery, “A. Perrino” Hospital, Brindisi, Italy; 2 Department of Pathology, “A. Perrino” Hospital, Brindisi, Italy; 3 Department of Neuroradiology, “A. Perrino” Hospital, Brindisi, Italy


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Langerhans cell histiocytosis (LCH) as a solitary lesion is a bone tumour uncommon in the cervical spine; furthermore adult age is rarely involved. The authors report the case of a 61 years-old woman with intractable cervical pain; radiological findings revealed an osteolytic lesion involving the C2 vertebra (axis). The patient underwent surgical treatment: biopsy and kiphoplasty of axis by anterior transoral approach and stabilization of cervical spine by posterior approach with placement of sublaminar Songer spinal cable system and titanium Hartshill cervical rectangle. Pathological examination was: Langerhans cell histiocytosis. A review of the literature confirmed the very rare localization of LCH in the cervical spine in adult age.

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