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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2011 October;170(5):301-5

Copyright © 2011 EDIZIONI MINERVA MEDICA

language: Italian

Cholelithiasis can be associated with systemic inflammatory diseases

Bertero D. 1, Camandona M. 2, Tarocco R. P. 3, Anania A. 3

1 S.S. Ambulatorio di Chirurgia Epato-Biliare, S.C.D.O. Chirurgia Generale 10, Azienda Ospedaliero Universitaria San Giovanni Battista di Torino, Torino, Italia 2 S.C.D.U. Chirurgia Generale III, Azienda Ospedaliero Universitaria, San Giovanni Battista di Torino, Torino, Italia 3 Ambulatorio di Reumatologia, S.C.D.U. Medicina Interna I, Torino, Italia, Azienda Ospedaliero Universitaria San Giovanni Battista di Torino, Torino, Italia


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Focal infection may affect remote sites, in which an inflammatory disorder due to immune factors can cause clinical manifestations, i.e. arthralgias, myalgias, erythema, swelling. Cholelithiasis is often associated with local infection. The potential role of cholelithiasis as a source of focal infection is still unknown. In a group of 19 patients affected with cholelithiasis and rheumatic disorders main acute phase proteins were higher than level found in a group of 23 patients affected with cholelithiasis alone. Patients of both groups underwent laparoscopic cholecystectomy. In 17 patients of the first group acute phase markers lowered 12 weeks after the laparoscopic cholecystectomy. However the modification was not statistically significant.

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