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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2010 October;169(5):255-60

Copyright © 2010 EDIZIONI MINERVA MEDICA

language: English

Endoscopic treatment of biliary complications after liver transplantation: analytic review

Tarantino I., Barresi L., Traina M., Gruttadauria S., Gridelli B.

1 Departement of Gastroenterology, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IsMeTT) University of Pittsburgh Medical Center Palermo, Italy 2 Department of Transplantation Surgery, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IsMeTT) University of Pittsburgh Medical Center, Palermo, Italy


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The data available shows that the rate of biliary complications in transplant recipients ranges between 8% and 35%, but this rate of complications is higher for living-related liver transplantation (LRLTx) than orthotopic liver transplantation (OLTx). Biliary complications may include: stricture, biliary leaks, stones or debris and Oddi dysfunction. The aim of this paper was to analyze the results of endoscopic treatments on biliary complications after liver transplantation. This article is a review of available published data on the results of endoscopic treatment of post transplant biliary complication. In patients with duct-to-duct anastomosis, the ERCP is safe and effective in the diagnosis and management of biliary complications and avoids in the majority of cases percutaneous transhepatic approach or surgical interventions; whether unsuccessful, the ERCP does not negatively affects the surgical intervention, so a trial of endoscopic therapy should be performed to delay or defer a post-transplantation surgical procedure.

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