Home > Journals > Gazzetta Medica Italiana Archivio per le Scienze Mediche > Past Issues > Gazzetta Medica Italiana Archivio per le Scienze Mediche 2006 October;165(5) > Gazzetta Medica Italiana Archivio per le Scienze Mediche 2006 October;165(5):227-9

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

ORIGINAL ARTICLES   

Gazzetta Medica Italiana Archivio per le Scienze Mediche 2006 October;165(5):227-9

Copyright © 2006 EDIZIONI MINERVA MEDICA

language: English

Energy change in formation of hemoglobin A1C in hemoglobin C disorders

Wiwanitkit V.

Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand


PDF


Hemoglobin A1C is the nonenzymatic glycated product of the Hb beta-chain at the valine terminal residue. Recently, the nature of energy consuming reaction in formation of HbA1C was reported and this was proposed as an underlying pathophysiology for poor nutritional status, muscle loss, and functional impairment poor control diabetic patients. Here, the author focuses on the energy change in formation of HbA1C in case of Hb C disorder, a common disorder in West Asia. In this work, the author calculated for the required energy for HbA1C per unit in Hb C disorder and found that the required energy range from the most to the least as Hb C disease, Hb C carrier and normal hemoglobin, respectively.

top of page