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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2002 April;161(2):97-9

Copyright © 2002 EDIZIONI MINERVA MEDICA

language: English

Fever of unknown origin with delay in the onset of SLE diagnostic criteria

Nocente R. 1, Gentiloni Silveri N. 2, Ceccanti M. 3, Bertazzoni G. 1, Magarò M. 2, Vastola M. 2, Gasbarrini G. 2

1 Emergency Department, University of Rome “La Sapienza”, Rome; 2 Institute of Internal Medicine, Catholic University, Rome; 3 Institute of VI Medical Clinic, University of Rome “La Sapienza”, Rome


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We re­port a ­case of a 47-­year-old man pre­sent­ing ­with fe­ver of un­known or­i­gin (FUO) and a ­high ESR. Laboratory ­tests ­showed CD4 lym­pho­cy­to­pe­nia and poly­clo­nal hy­per­gam­mag­lo­bu­li­ne­mia. The pa­tient was HIV neg­a­tive. He was aner­gic to ­skin ­tests: Merieaux ­test ­score was 0 (n.r. >10). Only 7 ­months af­ter the on­set of py­rex­ia, the pos­i­tiv­ity of 5/11 di­ag­nos­tic American Rheumatism Association (ARA) cri­te­ria for system­ic lu­pus er­y­them­a­to­sus (SLE) be­came ev­i­dent and SLE was di­ag­nosed. It is there­fore pos­sible ­that, ­while not in­clud­ed ­among SLE ARA cri­te­ria, fe­ver may be the on­ly pre­sent­ing ­sign of SLE for sev­er­al ­months.

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