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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2002 February;161(1):31-5

Copyright © 2002 EDIZIONI MINERVA MEDICA

language: Italian

Filariasis-like elephantiasis of the inferior limb in a woman with a cushingoid facies: adrenal pathology, parasitosis or lymphoma? A case report

Rosati E. 1, Aracri N. 1, Bottone A. 1, Cau C. 1, Balzani A. 2, Scotti E. 1

1 Azienda Ospedaliera S. Giovanni Addolorata - Roma, Divisione Medicina 4; 2 Policlinico Universitario «Umberto I» - Roma, Dipartimento di Dermatologia e Chirurgia Estetica


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A number of epidemiological studies over the past few years have highlighted a significant increase in the incidence of non-Hodgkin lymphoma (NHL). These tumoral forms appear in numerous clinical and histopathological variants. The initial clinical symptoms, which are often subtle and aspecific, frequently delay this complex diagnosis. The authors report the case of a young woman who was hospitalised in a department of internal medicine following spastic contractions of the lower limbs. The patient presented a cushingoid appearance and a huge lymphedema on the right leg complicated by skin infection and ulcerations caused by negligence due to a condition of dysthymia and severe socioeconomic and familial hardship. The presence of a non-Hodgkin lymphoma with large B cells was finally diagnosed; this represents the most common histopathological form. The patient was then transferred to the oncohematological ward where appropriate chemotherapy was commenced.

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