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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2000 August;159(4):143-8

Copyright © 2000 EDIZIONI MINERVA MEDICA

language: Italian

Bladder diverticula. Two clinical cases

Vrola V., Grassia C., Calabrese E., Tirino G., Marte A., Lama G.

Seconda Università degli Studi - Napoli, Dipartimento di Pediatria


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Bladder diverticula are protrusions through a weak point in the bladder muscle often near a ureteric orifice. Some of these diverticula are congenital, some acquired due to infravescical obstruction and some associated with other syndromes, such as Ehlers-Danlos syndrome, Williams syndrome or Menkes syndrome. The diagnosis of bladder diverticula was made by means of ultrasonography and micturating cystography. Two children with urinary tract disease presenting characteristic clinical and somatic features have been studied. Copper and ceruloplasmin levels in the serum were also performed. The elastin locus was investigated using FISH analyses. Biochemical studies showed normal copper and ceruloplasmin levels in the serum; FISH analyses didn’t demonstrate any elastin gene deletions. Therefore it is suggested that these are two infrequent cases of isolated bladder diverticula.

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