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Original Article   

Minerva Gastroenterology 2022 Jul 29

DOI: 10.23736/S2724-5985.22.03249-1

Copyright © 2022 EDIZIONI MINERVA MEDICA

language: English

Alcohol use disorder identification test renamed GLU GLU test in an area of nord-west of Italy. Preliminary descriptive results

Patrizia BALBINOT 1, 2, Carlo L. BOTTARO 3, Nicoletta GANDOLFO 4, Rinaldo PELLICANO 5, Gianni TESTINO 1, 2

1 Unit of Addiction and Hepatology/ Alcohological Regional Centre, ASL3 Liguria, c/o Polyclinic San Martino Hospital, Genova, Italy; 2 Centro Studi Mutual-Self-Help, Community Programs and Caregiver Training, ASL3 Liguria, Genova, Italy; 3 General Direction, ASL3 Liguria, Genova, Italy; 4 Department of Imaging, ASL3 Liguria, Genova, Italy; 5 Unit of Gastroenterology, Molinette Hospital, Torino, Italy


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INTRODUCTION: The first two causes of liver cirrhosis and hepatocellular carcinoma are alcoholic and dysmetabolic. In the early stages alcohol related liver disease (ALD) is silent. For this reason, more efforts should be made to identify early individuals with hazardous/harmful alcohol consumption (AC). Alcohol use disorder identification test (AUDIT) is a validated test.
METHODS: ASL3 (Ligurian Local Health Company 3) has included the AUDIT renamed GLU-GLU Test on its institutional website dedicated to citizens (https://www.asl3.liguria.it/). The renaming was carried out to bring citizens closer to the Test with greater ease. Especially younger citizens. At the end of the compilation of the test, the calculator provides the citizen with his score: in relation to his possible risk band, provides him with the appropriate advice. In case of a score higher than 7 ultrasonography and elastography (2D-SWE) is proposed.
RESULTS: from December 15, 2021 to July 15, 2022, 270 asymptomatic subjects requested a medical examination autonomously, without the indication of a health worker. In 167 the score found hazardous AC, in 65 harmful AC and in 38 alcohol addiction. In case of hazardous AC fibrosis grade 1-2 was evidenced in 16.7%, fibrosis grade 3 in 4.8% and fibrosis grade 4 in 3.6% of subjects. In case of harmful AC fibrosis grade 1-2 was evidenced in 37%, grade 3 in 9%, grade 4 in 6%. In this group an HCC nodule was diagnosed. In case of alcohol addiction, fibrosis grade 1-2 was evidenced in 73.6%, grade 3 in 10.5% and grade 4 in 10.5%.
CONCLUSIONS: this preliminary experience clearly tells us that it is possible to make an early diagnosis of fibrosis and HCC starting from the AC reported autonomously by citizens.


KEY WORDS: Alcohol related liver disease; Alcohol use disorder identification test; Early diagnosis

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