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Minerva Gastroenterologica e Dietologica 2018 September;64(3):235-50

DOI: 10.23736/S1121-421X.18.02483-2


language: English

Management of Helicobacter pylori in Piedmont, Italy

Davide G. RIBALDONE 1 , Dario MAZZUCCO 2, Sharmila FAGOONEE 3, Lucia CROCELLÀ 4, Alessandro LAVAGNA 4, Mario FRACCHIA 4, Gian P. CAVIGLIA 1, Daniele SIMONDI 5, Rodolfo ROCCA 2, Marco ASTEGIANO 6

1 Division of Gastroenterology, Department of Medical Sciences, University of Turin, Turin, Italy; 2 Division of Gastroenterology, Ospedale degli Infermi, Rivoli, Turin, Italy; 3 Institute for Biostructures and Bioimages (CNR) c/o Molecular Biotechnology Center, Turin, Italy; 4 Gastroenterology Unit, Mauriziano Umberto I Hospital, Turin, Italy; 5 Santa Croce e Carle Hospital, Department of Gastroenterol and Digestive Endoscopy, Cuneo, Italy; 6 Department of General and Specialistic Medicine, Gastroenterologia-U, Città della Salute e della Scienza di Torino, Turin, Italy


Helicobacter pylori (H. pylori) is a Gram-negative bacterium, usually acquired during childhood, whose natural habitat is the gastric lumen. H. pylori is accepted as the most important cause of gastritis and peptic ulcer in humans. Nevertheless, its important role in the pathogenesis of gastric cancer as well as in several extra-gastroduodenal diseases has been confirmed. The aim of this work is to discuss, for the first time in a single article, all publications concerning H. pylori infection arising from Piedmont region, Italy, where in 1893 Giulio Bizzozero was the first who observed and described spiral organisms in the stomach of animal models. A systematic review of all publications on the management of H. pylori in adults in Piedmont, based on a PubMed and a Scopus research from 1965 to 2017 was performed. The discussed aspects are the epidemiology, the study on gastric and extragastric diseases related to H. pylori, the diagnostic methods, the treatment of H. pylori infection, and the possibility of reinfection. In conclusions, with almost 70 publications, Piedmont has proudly maintained the tradition of the father of the H. pylori.

KEY WORDS: Liver cirrhosis - Culture - Diagnosis - Dyspepsia - Gastritis - Helicobacter - Ulcer

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