Home > Journals > Minerva Gastroenterologica e Dietologica > Past Issues > Minerva Gastroenterologica e Dietologica 2018 March;64(1) > Minerva Gastroenterologica e Dietologica 2018 March;64(1):84-93



Publication history
Cite this article as


A Journal on Gastroenterology, Nutrition and Dietetics

Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index




Minerva Gastroenterologica e Dietologica 2018 March;64(1):84-93

DOI: 10.23736/S1121-421X.17.02377-7


language: English

Internist, anesthesiologist and surgeon use of ketogenic diet

Lorenzo CENCI 1, Antonio PAOLI 1, Hesham R. OMAR 2, Prachiti DALVI 3, Enrico M. CAMPORESI 3 , Devanand MANGAR 3, Silvia QUARTESAN 1, Alberto FIORITO 1, Gerardo BOSCO 1

1 Physiological Laboratory, Department of Biomedical Science, University of Padua, Padua, Italy; 2 Department of Internal Medicine, Mercy Medical Center, Clinton, IA, USA; 3 TEAMHealth Anesthesia, Tampa General Hospital, Tampa, FL, USA


Ketogenic diet is being increasingly utilized in recent decades because of its success as an effective tool for short and intermediate-term weight loss. Promoting physiological ketosis from a drastically low carbohydrate diet is the fundamental basis for this diet regime. Though debated, these diets have been demonstrated to be effective, at least in the short- to medium terms, to manage excess weight, hyperlipidemia, and other cardiovascular risk factors. We reviewed the cardiovascular, metabolic, anesthetic, and postsurgical profiles in the literature and summarized technical issues of anesthesia and surgery along with long-term changes from published papers. Doubts with ketogenic diet were raised due to possible renal damage caused by significant excretion of nitrogen found in animal models, the effects of acidosis, and the concerns of increasing triglycerides and cholesterol levels. Though current literature supports the efficacy of very low carbohydrate keto-diets their potential negative effects on renal function and acidosis are debated. An increase in nitrogen excretion during protein metabolism in the postoperative period could lead to renal damage. Research on the value of ketogenic diets is emerging because of its value in weight loss and in managing other pathologies.

KEY WORDS: Ketogenic diet - Obesity - Diet, carbohydrate-restricted

top of page

Publication History

Issue published online: December 11, 2017
Manuscript accepted: February 3, 2017
Manuscript received: February 1, 2017

Cite this article as

Cenci L, Paoli A, Omar HR, Dalvi P, Camporesi EM, Mangar D, et al. Internist, anesthesiologist and surgeon use of ketogenic diet. Minerva Gastroenterol Dietol 2018;64:84-93. DOI: 10.23736/S1121-421X.17.02377-7

Corresponding author e-mail