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ORIGINAL ARTICLES  PERIOPERATIVE CARE IN LIVER TRANSPLANTATION 

Minerva Gastroenterologica e Dietologica 2010 September;56(3):253-60

Copyright © 2010 EDIZIONI MINERVA MEDICA

language: English

Anesthesia for liver transplantation: the experience of the University of Bologna in the meld era

Siniscalchi A., Miklosova Z., Spedicato S., Bernardi E., Zanoni A., Dante A., Pierucci E., Cimatti M., Riganello I., Aurini L., Bernabè L., Faenza S.

Department of Anesthesiology Alma Mater Studiorum University of Bologna, Bologna, Italy


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AIM: The hepatic cirrhosis is associated with an important cardiovascular alterations. In this report, we review our transplant center experience with liver transplantation in the Model for End-Stage Liver Disease (MELD) era, in particular this study investigate the relationship between severity of liver disease assessed by MELD score and postoperative events.
METHODS: Our retrospective review was performed on 242 cirrhotic patients underwent liver transplanation at the Department of Surgery and Transplantation of the University of Bologna. Biochemical and hemodynamic variables were evaluated by Swan-Ganz catherization. Dindo’s classification of postoperative complications was used for the evaluation of postoperative course.
RESULTS: Morbidity occurred in 158 patients (65.2%) and 13 patients died during the hospital stay. Considering the highest grade of complication occurred, non life-threatening complications occurred in the 47.9% of cases (116 patients) and life-threatening complications, excluding patient death, in 17.3% (42 patients). Patients with MELD >30 showed a longer ICU stay, tracheal intubation and in-hospital stay.
CONCLUSION: In conclusion MELD score is tightly related to postoperative complications.

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