THERAPEUTICAL NOTES   

Minerva Gastroenterologica e Dietologica 1999 March;45(1):59-76

Copyright © 1999 EDIZIONI MINERVA MEDICA

language: Italian

Topical beclomethasone dipropionate (BDP) in intestinal inflammatory diseases: the results of a multicentre trial

Borzio M., Borzio F., Milano G., Biraghi M., Cestari L., Ravelli P., de Franchis R., Vecchi M., Minoli G., Prada A., Curzio M., Galeone M., Toti G. L., Cacioli D., Megevand J.

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The authors assessed the efficacy and tolerability of BDP in an open protocol using rectal enemas and suppositories and in a double-blind protocol vs mesalazine using rectal enemas. A total of 47 patients suffering from ulcerous rectocolitis were enrolled in the study and treated for 42 days while undergoing endoscopic, histologic and clinical controls. In conclusion, the authors affirm that BDP may represent a useful new therapeutic instrument in the treatment of slight to moderately severe forms of inflammatory intestinal disease.