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CASE REPORT   

Esperienze Dermatologiche 2021 June;23(2):42-6

DOI: 10.23736/S1128-9155.21.00502-1

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English, Italian

A case of cutaneous angiosarcoma: dermoscopic analysis

Arianna PICCOLO , Mauro MAZZEO, Elisabetta BOTTI, Ilaria DE SIMONI, Luca BIANCHI

Department of Dermatology, Tor Vergata University, Rome, Italy


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Angiosarcoma (AS) is an aggressive subtype of soft-tissue sarcoma with a propensity for local recurrence and metastasis associated with a generally poor prognosis, unless diagnosed early. The disease is characterized by malignant proliferation of vascular or lymphatic endothelial cells. Here, we report the case of a 77-year-old man with a history of edematous violaceous flat infiltrating areas, prone to bleeding, in the left frontal-parietal-temporal region with involvement of the left ear and hemiface. Dermatoscopically, multiple red-purple-whitish structureless areas with white streaks were detectable. These tended to dispose around follicular openings in which a white-yellowish area, compatible with keratin mass, were observable. A background of multiple scales is furthermore observable. The histological examination highlighted the presence of vascular structures in irregular anastomoses desiccating collagen fibers, prominent atypical endothelium, sometimes pseudopapillary formation, with occasional mitosis. Immunohistochemical profile was CD34+, WT1-, HHV8-. The report was compatible with the diagnosis of angiosarcoma (AS). The patient died 4 days after histological diagnosis. We want to stress the importance of dermoscopic examination as it could provide additional data for a faster diagnosis.


KEY WORDS: Analysis; Hemangiosarcoma; Biopsy; Dermoscopy; Scalp

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