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CASE REPORT   

Esperienze Dermatologiche 2021 March;23(1):14-9

DOI: 10.23736/S1128-9155.21.00517-3

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English, Italian

Improving lip volume and contour through HYAL SYSTEM LIP, a novel hyaluronic acid-based lip filler

Ezio COSTA

Ezio Costa Clinic, Sona, Verona, Italy


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Lip volume and contour are among the determinants of the aesthetic perception of facial beauty. Accordingly, there is an increasing demand for lip augmentation procedures. Different techniques may be applied. Among these, augmentation through hyaluronic acid (HA)-based fillers is most preferred as it is easy to perform, scarcely invasive and quite well-tolerated. HA in fillers may differ for its molecular weight (MW) as well as for its degree of cross-linking and sidechain modification, aimed to change its filling effectiveness and persistence at the injection site. A novel HA-based formulation, HYAL SYSTEM LIP, is characterized by some features aimed to improve its performance. It contains 2.5% HA with two different MWs (1MDa/2MDa). Most is 1.4-butanediol diglycidyl ether (BDDE) cross-linked, improving the product texture and persistence, and the remaining is free, but interspersed among the cross-linked fraction, so that its release at the injection site is slow and its filling effect persistent over the time. The present report documents a case of a 30-year-old Caucasic woman (Fitzpatrick III, Glogau I and WSRS 2) who sought improvement of her lip contour and volume and was treated by retrograde linear injection of HYAL SYSTEM LIP, according to a two-point injection technique. After treatment, her Global Aesthetic Improvement Scale (GAIS) Score, determined by the treating clinician, was 5 (very much improved); at the 15-day control her GAIS was still 5 and no touch-up was needed. At the 6-month follow-up her GAIS score was 3 (improved). Her lips were well-contoured, well-projected and the vermillion line well-defined. No side effects were observed. HYAL SYSTEM LIP was effective in achieving persistent aesthetic improvement following lip augmentation.


KEY WORDS: Lip; Dermal fillers; Hyaluronic acid

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