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CASE REPORT   Freefree

Esperienze Dermatologiche 2020 December;22(4):49-52

DOI: 10.23736/S1128-9155.21.00510-0

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Remodeling atrophic scar in the medial anterior region of the knee with hyaluronan hybrid cooperative complexes: a case report

Nadezhda PAVLOVA

Private Practitioner, Como, Italy


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A scar is the product of the physiological wound repair process of the skin. When the healing process does not proceed as it should, the production phase could continue longer producing a hypertrophic scar, or shorter resulting in an atrophic scar and sometimes leading to inflammatory processes. In both cases, the aberrant scar formation can have important consequences, as body disfigurement or organ dysfunction, consequently efficacious treatment for scar prevention or remodeling are requested. During the wound healing process, an important role for the extracellular matrix reorganization is played by hyaluronic acid (HA) and the replenishment of HA by external administration is thought to represent a beneficial therapy for the aberrant scar management. The present case report is an example of conservative monotherapy, carried out with hybrid cooperative complexes (HCC) of hyaluronic acid injections to correct an iatrogenic atrophic scar. HCC treatment was able to significantly improve this defect, leading to the full correction of the scar at the end of follow-up visits (40 months) and supporting the role of HCC injections in the practice of dermatologist and surgeon to optimize the outcome of the wound healing process.


KEY WORDS: Hyaluronic acid; Wound healing; Cicatrix; Injections

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