REVIEW   Free

Esperienze Dermatologiche 2018 June;20(2 Suppl 1):9-11

DOI: 10.23736/S1128-9155.18.00464-8

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Centella asiatica: new microcirculatory and vascular application in preventive and clinical medicine

Gianni BELCARO ✉, Morio HOSOI, Shu HU, Mark DUGALL, Beatrice FERAGALLI, Roberto COTELLESE

IRVINE3 Labs, Department of Medical and Oral Sciences, and Biotechnologies, G. D’Annunzio University, Chieti, Italy

Centella asiatica (CA) is widely used as a medicinal herb in Indian, Chinese and other traditional Far-Eastern medicines. On the other hand, in Western medicine, CA is mainly used as highly purified standardized extracts enriched in triterpenes (e.g. TTFA, CAST). We discuss here our experience with the use of CA extracts with a focus on vascular conditions. Moreover, we report the preliminary results of a registry study showing their lack of pharmacological interaction with a number of antiplatelet and anticoagulation agents commonly used in clinical practice.

KEY WORDS: Centella asiatica extract - Vascular diseases - Microcirculation