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Esperienze Dermatologiche 2018 March;20(1):23-6

DOI: 10.23736/S1128-9155.18.00462-4

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Pyoderma gangrenosum secondary to Crohn’s disease: combined therapy with corticosteroids and cyclosporine

Marcella SIINO 1 , Clara ZICHICHI 1, Daniele RIZZO 1, Laura MICELI 2, Leonardo ZICHICHI 1

1 Unit of Dermatology, Sant’Antonio Abate Hospital, Erice, Trapani, Italy; 2 Unit of Anatomical Pathology, Sant’Antonio Abate, Erice, Trapani, Italy


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Pyoderma gangrenosum (PG) is a rare dermatosis characterized by intensely painful and rapidly progressive necrotic cutaneous ulcers. Still considered a condition of unknown etiology, it is associated with a variety of internal diseases, of which it constitutes a clinical manifestation. We report on a case of PG secondary to Crohn’s disease in a young woman, in whom a combination treatment consisting of systemic corticosteroids and cyclosporine has led to disease remission.


KEY WORDS: Pyoderma gangrenosum - Adrenal cortex hormones - Cyclosporine

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