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Esperienze Dermatologiche 2017 March;19(1):38-9

DOI: 10.23736/S1128-9155.17.00441-1

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Cutaneous B-cell lymphoma as Wolf’s isotopic response

Nicola di MEO, Sibil VERNONI, Silvia VICHI , Michela LONGONE, Serena FAGOTTI, Giusto TREVISAN

Unit of Dermatology and Venereology, Department of Dermatology, University of Trieste, Ospedale Maggiore of Trieste, Trieste, Italy


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A 73-year-old man comes to our attention for a lesion of the scalp. This lesion arose a few months after an ophthalmic Herpes Zoster involving the same region of the scalp. On examination there was an indolent purplish and erythematous nodule, localized in the fronto-parietal left region, with a diameter of 4x4 cm. The histology revealed a primary cutaneous B cell follicular lymphoma. The correlation between Herpes Zoster infection and B cell follicular lymphoma can be interpreted as a Wolf’s isotopic response, as already described in some cases. We present the case and a brief review of the literature.


KEY WORDS: Lymphoma, non-Hodgkin - Herpes zoster - scalp

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