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Esperienze Dermatologiche 2017 March;19(1):2-9

DOI: 10.23736/S1128-9155.17.00440-X

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: Italian

Syphilis: laboratory data interpretation

Massimo NACCA 1, Luigi BOCCIA 1 , Gelsomina RONZA 1, Luigi VALENZANO 2

1 Azienda Ospedaliera di Rilevanza Nazionale Sant’Anna e San Sebastiano, Caserta, Italia; 2 Istituto Dermatologico San Gallicano di Roma, Roma, Italia


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Syphilis is a complex and fearsome sexually transmitted infection, diagnostically difficult to interpret. Whenever they are present, typical clinical lesions help us in the diagnosis but, sometimes, occurrences at some stages of the disease, have a fleeting course. In these cases, the diagnosis of syphilis is indirect and serological tests are essential. We wanted to analyze the issue also considering the false biological positives and the greater specificity of some tests compared to others. We focused on the sensibility and the subsequent reliability of the tests in congenital syphilis, in neurosyphilis and in particular conditions like syphilis in pregnancy or in patients suffering from HIV.


KEY WORDS: Syphilis serodiagnosis - Treponema pallidum - Diagnosis

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