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Esperienze Dermatologiche 2016 September-December;18(3-4):158-62

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: Italian

Gluten and skin

Paola BETTO

Ospedale Civile San Bortolo, Vicenza, Italia


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Wheat allergy, celiac disease and non-celiac gluten sensitivity are among the diseases associated with reaction to gluten. Wheat allergy is an adverse reaction caused by an anomalous, IgE-mediated immunological reaction. Celiac disease is a chronic, systemic and immunomediated disease caused by a reaction to gluten; genetically predisposed subjects can improve by adopting a strict, life-long gluten free diet. Dermatitis herpetiformis, or Duhring’s Disease, can be considered a celiac disease of the skin; it presents with polimorphic lesions on the skin and the constant presence of alterations in the intestinal mucosa. Non-celiac gluten sensitivity (NCGS) is an intolerance to gluten that affects 6% of the population. It presents with intestinal and extra-intestinal symptoms. When it affects skin, it presents with eczema-like symptoms (40%) and with glossitis and aphthous stomatitis (10%). A diagnosis of exclusion is necessary. It is a very diverse picture that involves several sub-groups with selective activation of their natural immunity.

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