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Esperienze Dermatologiche 2014 December;16(4):197-203

Copyright © 2015 EDIZIONI MINERVA MEDICA

language: English, Italian

Human papillomavirus infection in HIV-1 infected patient: two clinical cases

Latini A. 1, Colafigli M. 1, Donà M. G. 1, Frasca M. 1, Ambrifi M. 1, Cota C. 2, Giuliani M. 1, Cristaudo A. 1

1 Dermatologia Infettiva e Allergologica, Istituto Dermatologico San Gallicano, Rome, Italy; 2 Anatomia Patologica, Istituto Dermatologico San Gallicano, Rome, Italy


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Anogenital human papillomavirus (HPV) infections and HPV-related neoplasia are very frequent among HIV-1 infected individuals. Studies show that antiretroviral (cART) therapy has brought about no reduction in the incidence of HPV-associated precancerous and cancerous lesions in this population. The cases of two HIV-positive patients who, respectively, presented perianal condylomatosis lesions and erythematous-papular-ulcerative lesions on the prepuce during antiretroviral therapy are described. The histopathological diagnosis, in both cases, was HPV-related bowenoid cancer.

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