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CASE REPORTS
Esperienze Dermatologiche 2011 June;13(2):65-7
Copyright © 2011 EDIZIONI MINERVA MEDICA
language: English, Italian
Plaque morphea in a patient with primary biliary cirrhosis
Berruti V. 1, Zanchini R. 1, Colasanti P. 1, Cordedda M. 1, Picciotti E. 2, Mozzillo R. 1
1 Unità Operativa di Dermatologia e Venereologia, Ospedale San Gennaro dei Poveri - ASL1, Napoli, Italia 2 Unità Operativa di Anatomia Patologica, Ospedale Pellegrini - ASL1, Napoli, Italia
Scleroderma is a chronic disease of unknown origin and characterized by cutaneous fibrosis. Two clinical entities are distinguished: localized scleroderma involving only the skin, with possible spread to the underlying muscuoloskeletal tissues; and systemic scleroderma, with a poorer prognosis and involvement of internal organs. Here we report the case of a 58-year-old woman with a 10-year history of primary biliary cirrhosis and a four-year history of infiltrated scleroatrophic plaques. Histologic examination of a lesion biopsy was diagnostic for localized scleroderma.