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Italian Journal of Emergency Medicine 2022 August;11(2):129-32

DOI: 10.23736/S2532-1285.22.00146-X

Copyright © 2022 THE AUTHORS

This is an open access article distributed under the terms of the CC BY-NC-ND 4.0 license which allows users to copy and distribute the manuscript, as long as this is not done for commercial purposes and further does not permit distribution of the manuscript if it is changed or edited in any way, and as long as the user gives appropriate credits to the original author(s) and the source (with a link to the formal publication through the relevant DOI) and provides a link to the license.

language: English

Anorexia nervosa: a possible trigger for recurrent Tako Tsubo Syndrome

Stefania CHERUBINI 1, Alessandro SCIAHBASI 2 , Andrea CIOLLI 1, Simona MINARDI 3, Marco REDIVO 4, Claudia CICCHINI 5, Valentina VALERIANO 5, Francesco R. PUGLIESE 5

1 Unit of Emergency Cardiology, Sandro Pertini Hospital, Rome, Italy; 2 Unit of Cardiology, Sandro Pertini Hospital, Rome, Italy; 3 University of L’Aquila, L’Aquila, Italy; 4 Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant’Andrea Hospital, Sapienza University, Rome, Italy; 5 Emergency Department, Sandro Pertini Hospital, Rome, Italy



We report the case of a severely underweight woman affected by anorexia nervosa, presenting with relapsing Tako Tsubo Syndrome (TTS) without any apparent emotional or physical stress trigger. After a first episode of TTS during a dispute with her neighbors, few years later a significant loss of body weight associated with mild anemia, electrolyte and blood glucose imbalance triggered a new episode. After the acute phase the patient fully recovered without sequelae. According to our case, patients with anorexia nervosa should be carefully controlled for glycemic and electrolyte fluctuations to avoid possible recurring episodes of TTS.


KEY WORDS: Anorexia nervosa; Takotsubo cardiomyopathy; Cardiomyopathies

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