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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2018 Mar 30

DOI: 10.23736/S0392-0488.18.06006-6

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Bullous pemphigoid: Italian guidelines adapted from EDF/EADV guidelines

Emanuele COZZANI 1, Angelo V. MARZANO 2, Marzia CAPRONI 3, Claudio FELICIANI 4 , Piergiacomo CALZAVARA-PINTON 5, on behalf of Cutaneous Immunology group of SIDeMaST 

1 Clinica Dermatologica Università di Genova, Genoa, Italy; 2 U.O.C. Dermatologia, Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; 3 SOS Malattie Rare Dermatologiche, U.O. Dermatologia I, P.O. Piero Palagi, Usl Toscana Centro, Università di Firenze, Florence, Italy; 4 Clinica Dermatologica Università di Parma, Parma, Italy; 5 Clinica Dermatologica, Università di Brescia, Brescia, Italy


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Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localised or generalised bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarises evidence-based and expert-based recommendations (S2 level).


KEY WORDS: Bullous pemphigoid - Italian guidelines

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Publication History

Article first published online: March 30, 2018
Manuscript accepted: March 27, 2018
Manuscript received: March 19, 2018

Cite this article as

Cozzani E, Marzano AV, Caproni M, Feliciani C, Calzavara-Pinton P; Cutaneous Immunology group of SIDeMaST. Bullous pemphigoid: Italian guidelines adapted from EDF/EADV guidelines. G Ital Dermatol Venereol 2018 Mar 30. DOI: 10.23736/S0392-0488.18.06006-6

Cutaneous Immunology group of SIDeMaST

Mauro ALAIBAC; Emiliano ANTIGA; Mariachiara ARISI; Danilo ASSALVE; Laura ATZORI; Graziella BABINO; Anna BALATO; Nicola BALATO; Tania BARBAGALLO; Anna BELLONI FORTINA; Enzo BERARDESCA; Emilio BERTI; Alessandro BORGHI; Valeria BRAZZELLI; Marta B. BRUMANA; Carlo BRUSATI; Stefano CACCAVALE; Giacomo CALDAROLA; Piergiacomo CALZAVARA-PINTON; Anna CAMPANATI; Raffaele D. CAPOSIENA CARO; Marzia CAPRONI; Ilaria COATI; Andrea CONTI; Antonio COSTANZO; Emanuele COZZANI; Annunziata DATTOLA; Clara DE SIMONE; Antonella DI CESARE; Vito DI LERNIA; Giovanni M. DI ZENZO; Luca FANIA; Giorgio FILOSA; Raffaele FILOTICO; Marta FUSANO; Antonia GERARDA GALLUCCIO; Giulia GANZETTI; Paolo GISONDI; Fabrizio GUARNERI; Katharina HANSEL; Sanja JAVOR; Michelangelo LA PLACA; Giulia LIBERATI; Viviana LORA; Angelo V. MARZANO; Giulia MERLO; Maria R. NASCA; Anna NIGRO; Cecilia NOAL; Annamaria OFFIDANI; Manuela PAPINI; Aurora PARODI; Annalisa PATRIZI; Andrea PESERICO; Stefano PIASERICO; Francesca PRIGNANO; Pietro QUAGLINO; Mariateresa ROSSI; Rosanna SATTA; Donatella SCHENA; Paolo SENA; Oriana SIMONETTI; Teodora R. STAN; Luca STINGENI; Marina TALAMONTI; Simona TAVECCHIO; Linda TOGNETTI; Annalisa VASCELLARO; Camilla VASSALLO; Marina VENTURINI; Anna ZAMPETTI; Arianna ZANCA

Corresponding author e-mail

claudio.feliciani@unipr.it