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A Journal on Dermatology and Sexually Transmitted Diseases

Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2017 Jul 11

DOI: 10.23736/S0392-0488.17.05697-8


language: English

How to improve adherence to treatment in patients with mild-to-moderate psoriasis? An expert opinion

Stefano PIASERICO 1 , Stefano MANFREDINI 2, Alessandro BORGHI 3, Paolo GISONDI 4, Massimiliano PAZZAGLIA 5, Giuseppe STINCO 6, Marina VENTURINI 7, Andrea CONTI 8

1 Dermatology Unit, Department of Medicine, University of Padova, Padova, Italy; 2 Department of Life Sciences and Biotechnology, Faculty of Medicine Pharmacy and Prevention, University of Ferrara, Master Course in Cosmetic Sciences and Technology, Laboratory of Health Products, Ferrara, Italy; 3 Section of Dermatology and Infectious Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 4 Department of Medicine, Section of Dermatology , University of Verona, Verona, Italy; 5 Division of Dermatology, Department of Specialized, Experimental and Diagnostic Medicine, University of Bologna, Bologna, Italy; 6 Department of Medicine, Institute of Dermatology, University of Udine, Udine, Italy; 7 Dermatology Unit, Department of Clinical and Experimental Science, University of Brescia, Brescia, Italy; 8 Dermatology Unit, Department of Head and Neck Surgery, AOU Policlinico di Modena, Modena, Italy


Topical treatments are frequently used for the therapy of psoriasis. However, they may be associated with poor adherence in clinical practice. Therapeutic adherence is affected by patient’s characteristics, as well as disease- and treatment-related factors; moreover, satisfaction with therapy, cosmetic acceptability and complexity of the treatment regimen do also play a role. Since low adherence could lead to treatment failure, it is crucial to elaborate effective strategies aimed at improving patient adherence and thus clinical outcomes in psoriasis. To this purpose, here we have addressed several aspects of dermatological treatment that impact on adherence such as selection of therapy, selection of vehicle, and physician-patient communication. In addition, possible practical measures to improve adherence have also been discussed. In this light, we report that the use of calcipotriol and betamethasone dipropionate (Cal/BD) fixed-combination gel may be associated with improved patients’ preference and better outcomes compared to similar formulations.

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Publication History

Article first published online: July 11, 2017
Manuscript accepted: May 25, 2017
Manuscript received: May 21, 2017

Cite this article as

Piaserico S, Manfredini S, Borghi A, Gisondi P, Pazzaglia M, Stinco G et al. How to improve adherence to treatment in patients with mild-to-moderate psoriasis? An expert opinion. G Ital Dermatol Venereol 2017 Jul 11. DOI: 10.23736/S0392-0488.17.05697-8

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