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Giornale Italiano di Dermatologia e Venereologia 2019 December;154(6):609-23

DOI: 10.23736/S0392-0488.19.06458-7

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

Italian Guidelines in diagnosis and treatment of alopecia areata

Alfredo ROSSI 1 , Marta MUSCIANESE 1, Bianca M. PIRACCINI 2, Michela STARACE 2, Marta CARLESIMO 1, Victor D. MANDEL 3, Aurora ALESSANDRINI 2, Stefano CALVIERI 1, Gemma CARO 1, Andrea D’ARINO 1, Alessandro FEDERICO 1, Francesca MAGRI 1, Flavia PIGLIACELLI 1, Graziana AMENDOLAGINE 4, Maria C. ANNUNZIATA 5, Maria C. ARISI 6, Stefano ASTORINO 7, Graziella BABINO 8, Federico BARDAZZI 2, Stefania BARRUSCOTTI 9, Anna BELLONI FORTINA 10, Alessandro BORGHI 4, Francesca BRUNI 2, Stefano CACCAVALE 8, Piergiacomo CALZAVARA-PINTON 6, Norma CAMELI 11, Michele CARDONE 1, Andrea CARUGNO 9, Rosa COPPOLA 12, Annunziata DATTOLA 13, Maria B. DE FELICI DEL GIUDICE 14, Antonella DI CESARE 15, Emi DIKA 2, Donato DI NUNNO 7, Roberto D’OVIDIO 16, Gabriella FABBROCINI 5, Claudio FELICIANI 14, Elisabetta FULGIONE 8, Marco GALLUZZO 13, Simone GARCOVICH 17, Valentina GARELLI 1, Cristina GUERRIERO 17, Katharina HANSEL 18, Michelangelo LA PLACA 2, Francesco LACARRUBBA 19, Viviana LORA 17, Elena MARINELLO 10, Matteo MEGNA 5, Giuseppe MICALI 19, Cosimo MISCIALI 2, Paola MONARI 6, Giuseppe MONFRECOLA 5, Iria NERI 2, Annamaria OFFIDANI 20, Gloria ORLANDO 10, Manuela PAPINI 18, Annalisa PATRIZI 2, Stefano PIASERICO 10, Niccolò RIVETTI 9, Oriana SIMONETTI 20, Teodora R. STAN 10, Luca STINGENI 18, Marina TALAMONTI 13, Francesco TASSONE 17, Lucia VILLA 16, Colombina VINCENZI 2, Maria C. FORTUNA 1

1 Division of Dermatology, Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy; 2 Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy; 3 Unit of Dermatology, Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy; 4 Section of Dermatology and Infectious Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 5 Section of Dermatology, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy; 6 Department of Dermatology, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy; 7 Unit of Dermatology and Venereology, Celio Military Hospital, Rome, Italy; 8 Unit of Dermatology, Nuovo Policlinico, Luigi Vanvitelli University of Campania, Naples, Italy; 9 Unit of Dermatology, S. Matteo University Polyclinic, IRCCS and Foundation, Pavia, Italy; 10 Unit of Dermatology, Department of Medicine - DIMED, University of Padua, Padua, Italy; 11 San Gallicano Dermatological Institute (IRCCS), Rome, Italy; 12 Campus Bio-Medico University (Hospital), Rome, Italy; 13 Department of Dermatology, Tor Vergata Polyclinic and University, Rome, Italy; 14 Section of Dermatology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy; 15 Section of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy; 16 Private Practitioner, Bari, Italy; 17 Institute of Dermatology, A. Gemelli University Polyclinic, IRCCS and Foundation, Sacred Heart Carholic University, Rome, Italy; 18 Section of Dermatology, Department of Medicine, University of Perugia, Perugia, Italy; 19 Department of Dermatology, University of Catania, Catania, Italy; 20 Unit of Dermatology, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, Italy



Alopecia areata (AA) is an organ-specific autoimmune disorder that targets anagen phase hair follicles. The course is unpredictable and current available treatments have variable efficacy. Nowadays, there is relatively little evidence on treatment of AA from well-designed clinical trials. Moreover, none of the treatments or devices commonly used to treat AA are specifically approved by the Food and Drug Administration. The Italian Study Group for Cutaneous Annexial Disease of the Italian Society of dermatology proposes these Italian guidelines for diagnosis and treatment of Alopecia Areata deeming useful for the daily management of the disease. This article summarizes evidence-based treatment associated with expert-based recommendations.


KEY WORDS: Alopecia areata; Guideline; Autoimmunity

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