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Giornale Italiano di Dermatologia e Venereologia 2019 February;154(1):42-9

DOI: 10.23736/S0392-0488.18.06113-8

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Pathogenesis and causations of systemic contact dermatitis

Chandler W. RUNDLE 1, Brian C. MACHLER 2, Sharon E. JACOB 3

1 School of Medicine, Loma Linda University, Loma Linda, CA, USA; 2 Department of Dermatology, NYU Ronald O. Perelman School of Medicine, New York, NY, USA; 3 Department of Dermatology, Loma Linda University, Loma Linda, CA, USA



Systemic contact dermatitis (SCD) describes a hypersensitivity reaction following systemic re-exposure of the inciting allergen in previously sensitized individuals. Plants, drugs, and metals are the most common causes of SCD. In individuals with obstinate dermatitis, it is imperative to deliver history-focused patch testing with subsequent avoidance and elimination of the compound.


KEY WORDS: Dermatitis, contact - Hypersensitivity - Etiology

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